The Evaluation Of Surrogate Endpoints-..
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Both humanitarian and commercial considerations have spurred intensive search for methods to reduce the time and cost required to develop new therapies. The identification and use of surrogate endpoints, i.e., measures that can replace or supplement other endpoints in evaluations of experimental treatments or other interventions, is a general strategy that has stimulated both enthusiasm and skepticism. This book offers a balanced account on this controversial topic. The text presents major developments of the last couple of decades, together with a unified, meta-analytic framework within which surrogates can be evaluated from several angles. Methodological development is coupled with perspectives on various therapeutic areas. Academic views are juxtaposed with standpoints of scientists working in the biopharmaceutical industry as well as of colleagues from the regulatory authorities.
| ISBN | 9780387202778 |
| Autor(a) | Burzykowski, Tomasz |
| Editora | Springer Publishing |
| Ano de edição | 2005 |
| Páginas | 410 |
| Acabamento | Capa Dura |
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