The Rho Gtpases In Cancer-..
-
- 1x de R$ 1.410,92 sem juros
- 2x de R$ 705,46 sem juros
- 3x de R$ 470,30 sem juros
- 4x de R$ 352,73 sem juros
-
R$ 1.340,37
-
R$ 1.410,92
Channing Der and colleagues provide an encyclopedic overview of the Rho GTPases, providing enough detail to make any reader well-versed in the Rho field. Finally, Sofia Merajver's laboratory provides an overview, which details the roles of the Rho proteins in cancer progression. She provides us with the history of the study of the Rho GTPases, their regulatory and effector proteins in cancer and gives us a benchmark of where the field is today. The second section of the book details the current knowledge of the Rho regu- tory proteins in cancer progression: aberrant expression and activation of these proteins leads to dysfunctional Rho signaling and a cancer phenotype. Gary Bokoch's laboratory has provided a detailed overview of the role of Rho guanine dissociation inhibitors (GDIs) in cancer. These molecules are involved in preventing the Rho protein from associating with the inner plasma membrane and exchanging GDP for GTP, and thus becoming active. Next, Tozu Kazasa's labo- tory has worked on the link between heterotrimeric G proteins and Rho activation via the RGS-RhoGEFs. This aspect of Rho activation is particularly interesting in that heterotrimeric G proteins and their associated G-protein-coupled receptors are attractive and attainable therapeutic targets. Dan Billadeau's laboratory has worked extensively on the Vav RhoGEFs, which are potent oncogenes in their own right.
| ISBN | 9781489982865 |
| Autor(a) | Van Golen, Kenneth |
| Editora | Springer Publishing |
| Ano de edição | 2014 |
| Páginas | 206 |
| Acabamento | Brochura |
| Dimensões | 23,40 X 15,60 |
Produtos relacionados
-
Bacterial Virulence Factors And Rho Gtpases-..R$ 1.410,92até 4x de R$ 352,73 sem jurosou R$ 1.340,37 via Pix -
Bacterial Virulence Factors And Rho Gtpases-..R$ 1.410,92até 4x de R$ 352,73 sem jurosou R$ 1.340,37 via Pix
Categorias
Conteúdo
Sobre a loja
Myre Livraria, sua livraria online especializada em importação e revenda de livros nacionais e internacionais. Oferecemos uma vasta seleção de materiais didáticos de alta qualidade para aprender inglês, espanhol, francês, alemão e muito mais. Aproveite preços competitivos e entrega rápida em todo o Brasil
Pague com
Selos
Myre Editora Ltda. - CNPJ: 50.295.718/0001-20 © Todos os direitos reservados. 2026
